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"At the same time, we want to closely monitor these patients, because changes in - probably benign' lesions occasionally mean cancer, and we want to detect the cancers as early as possible" Radiologists can, with confidence, recommend a six-month follow-up diagnostic mammogram rather than an immediate biopsy for patients with "probably benign" breast lesions, a new study emphasizes. via Newswise

Radiologists can, with confidence, recommend a six-month follow-up diagnostic mammogram rather than an immediate biopsy for patients with "probably benign" breast lesions, a new study emphasizes.The study found that six-month short-interval follow-up examinations had an 83% sensitivity, which is similar to the sensitivity of other diagnostic mammograms, said Erin J. Aiello Bowles, MPH, lead author of the study from the Group Health Center for Health Studies.

You might think that if you were diagnosed with breast cancer, then the first course of action would be to determine your treatment options and get started right away. But...

A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, according to research by scientists at Emory University's Winship Cancer Institute.The results are published in the May 9, 2008 issue of the journal Molecular Cell.Most breast cancers contain estrogen receptors, which enable them to grow in the presence of the hormone estrogen.

IntroductionLevels of insulin-like growth factor (IGF)-I and its main binding protein (IGFBP-3) have been associated with breast cancer risk among premenopausal women. However, associations of IGFBP-3 levels with breast cancer risk have been inconsistent, possibly due to the different predominant forms of circulating IGFBP-3 (intact versus fragmented) that were measured in these studies. Here, we examine the association of breast cancer risk factors with intact and total IGFBP-3 levels. Methods: This cross-sectional study includes 737 premenopausal women recruited at screening mammography. Plasma IGF-I, intact and total IGFBP-3 levels were measured by ELISA methods. Percent and absolute breast density were evaluated using a computer-assisted method. The associations were evaluated using generalized linear models and Pearson's (r) or Spearman's (rs) partial correlation coefficients. Results: Means +/- standard deviations of intact and total IGFBP-3 levels (ng/mL) were 1044 +/- 234 and

Depression and Anxiety Are Common, But So Is HelpA diagnosis of breast cancer is one of the most devastating things a woman can hear. After such shocking news, it is...

Title: Breast cancer Tends to Grow Faster in Younger WomenCategory: Health NewsCreated: 5/9/2008 2:00:00 AMLast Editorial Review: 5/9/2008

"The problem is that a significant fraction of estrogen receptor positive tumors don't respond to tamoxifen" A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, according to research by scientists at Emory University's Winship Cancer ... via Huliq.com

IntroductionTreatment with estrogen and progesterone mimics the protective effect of parity on mammary tumors in rodents and depends upon the activity of p53. The following experiments tested whether exogenous estrogen and progesterone prime p53 to be more responsive to DNA damage and if these pathways confer resistance to mammary tumors in a mouse model of Li-Fraumeni syndrome. Methods: Mice that differ in p53 status (Trp53+/+, Trp53+/-, Trp53-/-) were treated with estrogen and progesterone (E+P) for 14 days, then were tested for p53-dependent responses to ionizing radiation. Responses were also examined in parous and age-matched virgins. The effects of hormonal exposures on tumor incidence were examined in BALB/c-Trp53+/- mammary tissues. Results: Nuclear accumulation of p53 and apoptotic responses were increased similarly in the mammary epithelium from E+P-treated and parous mice compared to placebo and age-matched virgins. This effect is sustained for at least 7 weeks after E+

Main Category: women's health / Gynecology Also Included In: Pharmacy / Pharmacist Article Date: 08 May 2008 - 7:00 PDT rate article Wal-Mart Stores on Monday announced that it is adding several women's ... via Medical News Today