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(Georgetown University Medical Center) Researchers at Georgetown University Medical Center have discovered a novel way in which breast cancer cells become resistant to tamoxifen, the world's largest-selling breast cancer prevention and treatment drug. They say the findings could provide a way to identify tamoxifen users who are no longer benefitting from the drug, allowing doctors to try another therapy option sooner.

(American Association for cancer Research) Women who experience severe gestational hypertension may give birth to boys at lower risk for testicular cancer, although the exact reasons why are still unclear, according to a paper published in the Nov. 1, 2008, issue of Cancer Research, a journal of the American Association for Cancer Research.

Epeius Biotechnologies Corporation announced the expansion of clinical trials using intravenous Rexin-G for pancreatic cancer and breast cancer in Manhattan, new york. Rexin-G is the world's first tumor-targeted genetic medicine that is designed to seek out and destroy both primary tumors and metastatic cancers that have spread throughout the body.

Charles J. Yeo, M.D., Samuel D. Gross Professor and Chair, Department of Surgery at Jefferson Medical College of Thomas Jefferson University, announces the establishment of the new Jefferson Pancreas Tumor Registry (JPTR). "The purpose of the registry is to further study whether pancreatic cancer occurs more frequently in families with a history of the disease," said Dr. Yeo, who is the principal investigator of JPTR.

The Connecticut Department of Public health (DPH) today announced an online database on cancer incidence and mortality rates for Connecticut and each of the eight counties in Connecticut. The "Cancer Incidence and Mortality in Connecticut" resource produces tables with cancer rates for each of the state's counties, and county maps colored according to the range of cancer rates for each type of cancer.

The association of DM2 with solid tumors, and particularly with HCC, has been long suspected and several studies have reported increased mortality rates for neoplastic diseases in patients with DM2. However, the temporal relationship between the onset of diabetes and development of HCC, and the clinical and metabolic characteristics of patients with DM2 and HCC have not been well examined.

The sequencing of the human genome has opened the door for proteomics by providing a sequence-based framework for mining proteomes. As a result, there is intense interest in applying proteomics to foster a better understanding of cancer processes, develop new biomarkers for diagnosis and early detection of cancer. Gastric carcinoma is one of the most common malignancies worldwide and is the most common cause of cancer-related death in China.

Expression of Livin in fresh esophageal cancer tissues was detected by immunohistochemistry (IHC), Western blotting and reverse transcriptase-polymerase chain reaction (RT-PCR), VEGF by Its correlation Western blotting and RT-PCR. Livin positivity was also significantly correlated with tumor stages, increasing with tumor progression. Expression of Livin and VEGF increased with the process of esophageal carcinoma.

TomoTherapy Incorporated (NASDAQ: TOMO) announced today that Technical University of Munich, Germany, recently welcomed 175 radiation oncology experts from 16 countries to the 'International Conference on the Clinical Use of TomoTherapy'. The two-day event featured 35 technical talks from doctors and physicists.

(University of California - Davis - health System) In trying to find out why HER2-positive breast cancer can be more aggressive than other forms of the disease, UC Davis Cancer Center researchers have surprisingly discovered that HER2 itself is the culprit.