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An over-the-counter vitamin in high doses prevented memory loss in mice with Alzheimer's disease, and UC Irvine scientists now are conducting a clinical trial to determine its effect in humans. Nicotinamide, a form of vitamin B3, lowered levels of a protein called phosphorylated tau that leads to the development of tangles, one of two brain lesions associated with Alzheimer's disease.

An over-the-counter vitamin in high doses prevented memory loss in mice with some aspects of Alzheimer's disease, according to a paper published today (5 November) in the Journal of Neuroscience. The vitamin also strengthened scaffolding along which information travels in brain cells, helping to keep neurons alive and further preventing symptoms in mice genetically wired to develop Alzheimer's.

Health Secretary Alan Johnson pledged to speed up the process of approving new drugs for use on the NHS with the aim of minimising the numbers forced to pay for treatment. The widely-trailed new package of measures, which overturns the ban on patients paying for drugs while accessing NHS care, is designed to clearly separate private care from that provided by the NHS.

Neglect or abuse can be minimised by high quality care services, according to a new CSCI report released today. Safeguarding: A study of the effectiveness of arrangements to safeguard adults from abuse found that councils with higher overall quality ratings are more likely to have better safeguarding practices in place. This resulted in less abuse and more support to those who experienced abuse.