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Plethora Solutions Holdings PLC ("Plethora" or the "Company", AIM: PLE), the specialist developer of products for the treatment and management of urological disorders, announces that its European Phase III double-blind placebo controlled study of PSD502 for the treatment of premature ejaculation (PE) has met its three co-primary endpoints of Intra-vaginal Ejaculation Latency Time ('IELT') and Index of Premature Ejaculation ('IPE'; Ejaculatory Control and Sexual Satisfaction domains).

A collaborative study led by investigators from Massachusetts General hospital (MGH) is giving what may be the first look at how interactions between genes underlie a key symptom of schizophrenia, impaired working memory. Functional imaging studies reveal how a combination of common variants in two genes is associated with reduced activity of important brain structures in schizophrenia patients but not in normal controls. The report has been released online in the Early Edition of the Proceedings of the National Academy of Sciences. read more

Brain scans of bullies show disruption in natural empathetic response. Unusually aggressive youth, who are bullies, may actually enjoy inflicting pain on others, research using brain scans at the University of Chicago shows. Scans of the bullying brains showed that an area that is associated with rewards was highlighted when the youth watched a video clip of someone inflicting pain on another person. Youth without the unusually aggressive behavior did not have that response, the study showed. read more

A new study using functional magnetic resonance imaging (fMRI) reports bullies may enjoy seeing someone else in pain. Dr. Benjamin Lahey, a psychologist at the University of Chicago was the lead researcher in a study published in Biological Psychology. By watching the brain scans as teens viewed others getting hurt, they saw changes that showed they got pleasure out of seeing pain inflicted on another person. read more

A specific population of brain cells could provide a target for developing new medications aimed at helping people learn to mute the fears underlying anxiety disorders, according to NIMH-supported scientists. Background read more