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Whole Grain ProductsPhoto © USDAWe like brown bread at my house. It tastes good and has a texture that will stand up to many different sandwich fillings, or...

IntroductionInterleukin (IL)-17 plays an important role in autoimmunity, promoting auto-immunity, inflammation and invasion in multiple sclerosis, rheumatoid arthritis and type-I diabetes. However, its role in cancer is unclear as there are few studies examining IL-17 protein expression in cancer. Therefore, we examined IL-17 protein expression in human breast cancer and modelled its potential biological significance in vitro. Methods: Immunohistochemistry was used to determine IL-17 expression in breast cancers. Matrigel invasion assays were employed to examine the effect of IL-17 on cancer cell invasion by a panel of breast cancer cell lines. The role of matrix metalloproteinases (MMPs) was investigated with selective antagonists and immunoassays for MMPs-2, 3, 9 and tissue inhibitor of MMP (TIMP1). Results: IL-17 expressing cells with macrophage morphology were identified in the peri-tumoural area of a proportion of patients (8/19). Macrophages were confirmed by CD68 staining

HealthDay - MONDAY, Nov. 17 (HealthDay News) -- The risk of breast cancer for a woman with a strong family history is four times higher than that of the general population -- even if she does not carry one of the breast cancer-linked mutations of the BRCA gene, a new study finds.

British researchers have discovered a possible explanation for why some female breast cancer patients being treated with tamoxifen -- the most commonly used breast cancer drug -- are resistant to the treatment, increasing their risk that tumors will return, according to a study published in the journal

HealthDay - MONDAY, Nov. 17 (HealthDay News) -- After a mastectomy, wealthier women are more likely to have immediate breast reconstruction than their poorer counterparts, Johns Hopkins University researchers report.

Title: Lung cancer patients Get Blamed for Their DiseaseCategory: health newscreated: 11/15/2008 2:00:00 amlast Editorial review: 11/17/2008

Title: Swollen Lymph NodesCategory: Diseases and ConditionsCreated: 11/17/2008Last Editorial review: 11/17/2008