health - "develop"

AP - National Guard and Reserve combat troops in Iraq and Afghanistan are more likely to develop drinking problems than active-duty soldiers, a new military study suggests. The authors speculate that inadequate preparation for the stress of combat and reduced access to support services at home may be to blame.

A drug developed to prevent brittle bone disease could dramatically slow the growth of breast cancer tumours, new research suggests.

Oxygen Biotherapeutics, Inc. (OTCBB:OXBO) announced that the company has developed a gel-like form of Oxycyte® that it intends to investigate as a topical application for open wounds, abrasions and burns. Oxycyte is the Company's perfluorocarbon (PFC) therapeutic oxygen carrier. The innovation is based on technologies in-licensed earlier this year from Virginia Commonwealth University.

Diakron Pharmaceuticals, Inc. announced today the signing of an exclusive license agreement for a novel investigational oral anticoagulant drug candidate discovered and developed through Phase I clinical trials by Merck & Co. Inc. Under the terms of the agreement, Diakron has the exclusive rights to develop, and, if approved, market and distribute the compound worldwide.

Groundbreaking research to enable rapid diagnosis of bird flu - including the deadly H5N1 strain which can be fatal if passed on to humans - is being developed with the help of Nottingham Trent University.

Polo-like kinase 1 (Plk1) is a member of a family of serine/threonine kinases involved in the regulation of cell-cycle progression and cytokinesis and is an attractive target for the development of anticancer therapeutics. A zebrafish homolog of the human Plk1 (hPlk1) kinase domain (KD) was identified that can be expressed in large quantities in bacteria and crystallizes readily, whether in a wild-type form or as a variant containing the activating Thr196?Asp substitution, in one space group and under similar conditions both in the absence and presence of active-site compounds. This construct was validated by testing a panel of hPlk1 inhibitors against human and zebrafish proteins and it was shown that the selected small molecules inhibited the homologs with a high degree of correlation. Crystal structures of ligand-free wild-type and activated zebrafish Plk1 (zPlk1) KDs revealed the organization of the secondary structural elements around the active site and demonstrated that the acti

The Honourable Chuck Strahl, Minister of Indian Affairs and Northern Development and Federal Interlocutor for Métis and Non-Status Indians, on behalf of the Honourable Tony Clement, Minister of health, announced today reforms that will help improve the delivery of Aboriginal health care in Nova Scotia.

Scientists at the National Institutes of health (NIH) have found a mechanism in the immune systems of mice that can lead to the development of autoimmune disease when turned off. The findings shed light on the processes that lead to the development of autoimmunity and could also have implications for the development of drugs to increase the immune response in diseases such as cancer and HIV. The study paper appears online today in the journal 'Nature.'

Chronic hepatitis B infects 400 million people worldwide, many of them children. Even with three effective vaccines available, hepatitis B remains a stubborn, unrelenting health problem, especially in Africa and other developing areas. The disease and its complications cause an estimated 1 million deaths globally each year. (Source: News-Medical News Feed)

Molecular chaperones are proteins that help other proteins fold into their characteristic 3D shape. The chaperone CCT (Chaperonin Containing TCP-1) plays a vital role in folding cellular cytoskeletal proteins that are intimately involved in cell structure, division and locomotion. The mechanism of CCT action is important to current cancer research and is not fully understood.