health - "cancer"

A team of researchers at West Virginia University has shown that U.S. immigrants from India and Pakistan take on the habits of their adopted country, increasing their risks of prostate cancer among male ...

The Louisiana cancer Foundation is known for promoting quality of life for cancer patients and their families while also providing the citizens of Louisiana with accurate and up-to-date information on ...

What we are learning about the interplay of hormones, breast cancer, chemotherapy and the pregnant body.

Trisha Goddard. Photo EDP library JON WELCH 30 August 2008 07:00 TV presenter Trisha Goddard has described the 'hell' of chemotherapy side-effects as she battles breast cancer.

New research strongly suggests that a mix of preventative agents, such as those found in concentrated black raspberries, may more effectively inhibit cancer development than single agents aimed at shutting down a particular gene.Researchers at the Ohio State University Comprehensive cancer Center examined the effect of freeze-dried black raspberries on genes altered by a chemical carcinogen in an animal model of esophageal cancer.read more

The hypothesis that cancer stem cells are responsible for the chemo-resistant and metastatic phenotypes of many breast cancers has gained support using cell sorting strategies to enrich for the tumor-initiating population of cells. However, the mechanisms regulating the cancer stem cell pool are less clear. Two recent publications suggest that loss of p53 permits expansion of presumptive cancer stem cells in mouse mammary tumors and human breast cell lines. These results add restriction of cancer stem cells as a new tumor suppressor activity attributed to p53.

Researchers at the Moores cancer Center at the University of California, San Diego (UC SD) in La Jolla have found evidence explaining why a common chemotherapy drug, cisplatin, may not always work for every cancer patient. They have shown that when a variant version of a key protein that normally causes cell death is active, patients may be resistant to the cancer-killing drug.

IntroductionPatients with primary operable estrogen receptor negative (ER-) breast cancer account for approximately 30% of all cases and generally have worse prognosis than ER+ patients. Nevertheless, a significant proportion of ER- cases have favourable outcome and could potentially benefit from a less aggressive course of therapy. Identification of such good prognosis patients however remains difficult and at present only possible through histopathological factors.Methods:Building on a previously identified 7-gene prognostic IR-module for ER negative breast cancer, we develop a novel statistical tool based on Mixture Discriminant Analysis in order to build a classifier that can accurately identify ER- patients with good prognosis.Results:We report the construction of a 7-gene expression classifier that accurately predicts, across a training cohort of 183 ER- tumors and six independent test cohorts (a total of 469 ER- tumors), ER- patients of good prognosis (in test sets, average

New data on whether the popular cholesterol drugs Zetia and Vytorin increase risk of cancer will be one of the highlights of a huge European conference of heart specialists opening Saturday.

CELSION CORPORATION (NASDAQ: CLSN) announced today that the interim results from its second Phase I liver cancer confirmation study of ThermoDox® used in combination with Radio Frequency Ablation (RFA) for the treatment of patients with primary and metastatic liver cancer will be presented at a Poster Presentation session at the International Liver cancer Association (ILCA) Annual Conference in Chicago, IL, from September 5-7, 2008.