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Toward prediction of binding affinities between the mhc protein and its peptide ligands using quantitative structure-affinity relationship approach. Toward prediction of binding affinities between the MHC protein and its Peptide ligands using quantitative structure-affinity relationship approach. Protein Pept Lett. 2008;15(10):1033-43 Authors: Tian F, Lv F, Zhou P, Yang Q, Jalbout AF It is important but challenging to determine the binding specificity of MHC-peptide interactions accurately and to predict their binding affinity quantitatively. In this paper, we discuss the application of an effective amino acid descriptor to model and predict the binding affinities between the MHC protein and its peptide ligands. This amino acid descriptor was derived from 23 electronic properties, 37 steric properties, 54 hydrophobic properties and 5 hydrogen bond properties of coded amino acids using principal component analysis (PCA), cal... medworm.comCircumcision Reduces the Risk of HIV Infection in Heterosexual Men A new U.S. study has found that being circumcised significantly reduced the risk of HIV infection in heterosexual African American men known to have been exposed to the virus. The findings complement those of recently reported clinical trials in Africa, where interventional use of adult male circumcision similarly reduced the risk of HIV infection in heterosexual men. The findings of the new study, along with similar results from other studies, suggest that circumcision may protect other heterosexual males in the U.S.read more eMaxHealthSmoking Is Linked to Increased Risk for Colorectal Cancer, Death An analysis of previous studies indicates that smoking is significantly associated with an increased risk for colorectal cancer and death, according to an article in the December 17 issue of JAMA. topix.netHIV/AIDS "hidden but growing" problem in the Philippines (AFP) "I came out to show people we are normal," says AIDS worker Roberto Ruiz, who is fighting the social stigma that HIV/AIDS still carries in the Philippines. yahoo.comWashington Post Examines History Of Whitman Walker Clinic The Washington Post on Tuesday examined the history of the Whitman-Walker Clinic, a not-for-profit community health organization in Washington, D.C., that runs special programs for people living with HIV/AIDS. Medical News TodayNew genetic analysis might boost breast cancer care Title: New Genetic Analysis Might Boost Breast Cancer CareCategory: Health NewsCreated: 12/17/2008 2:00:00 AMLast Editorial Review: 12/17/2008 (Source: MedicineNet Osteoporosis General) MedWorm Message: Find out how you can get your message across here by sponsoring this MedWorm news feed. Med WormHiv can penetrate a woman`s healthy genital skin Title: HIV Can Penetrate a Woman's Healthy Genital SkinCategory: Health NewsCreated: 12/17/2008 2:00:00 AMLast Editorial Review: 12/17/2008 (Source: MedicineNet Osteoporosis General) Med WormCARIBBEAN: Despite Successes, Too Many Dying of AIDS PORT OF SPAIN, Dec 9 (IPS) - Every day, 55 people in the Caribbean are infected with the HIV virus and 38 of them die of the disease. That's 20,000 new infections and 14,000 deaths annually. ispnews.netPoll Examines HIV/AIDS Testing, Awareness, Stigma In Russia About 23% of Russians responding to a recent poll have taken HIV tests this year, according to the poll that examined HIV testing, awareness, treatment options and stigma conducted by the All-Russia Public Opinion Center, ITAR-TASS World Service Reports. The poll, conducted nationwide in April and May 2008, surveyed 1,600 people in 140 Russian settlements. Medical News TodayKenya`s HIV Transmission Law Divides Government, Advocates, IRIN/PlusNews Reports A new law in Kenya -- which has been approved but not yet implemented -- is intended to prevent willful transmission of HIV/AIDS, but some advocates and government agencies are divided on its possible implications, IRIN/PlusNews reports. Medical News Today1 2 |
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