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[daily clinical practice: biological testing in osteoporosis.] [Daily clinical practice: Biological testing in osteoporosis.] J Soc Biol. 2008;202(4):275-80 Authors: Souberbielle JC, Cormier C Although biological testing has nothing to do with the diagnosis of osteoporosis, it can help the physician to: 1) identify secondary causes of low bone mass and/or fracture. There is however currently no consensus to define the biochemical parameters to be measured in this case. The cost-effectiveness of the biological evaluation, that is, measuring a minimum of parameters to detect a maximum of anomalies needs to be considered. Most experts agree that malignancy and especially a myeloma should be ruled out, and that an evaluation of calcium/phosphorus metabolism including the measurement of serum calcium, phosphate, PTH and 25 hydroxy-vitamin D sho... MedWorm Message: Find out how you can get your message across here by sponsoring this MedWorm news feed. Med Worm[epidemiology of osteoporosis.] [Epidemiology of osteoporosis.] J Soc Biol. 2008;202(4):251-5 Authors: Chapurlat R Osteoporosis leads to fragility fractures. Fracture incidence increases after the menopause among women and with age in both genders. More than 40 % of women will sustain at least one fragility fracture after the age of 50. Many risk factors have been described, including age, familial history of fracture, low bone mineral density, personal history of fracture, smoking and low body mass index. Fracture incidence is increasing worldwide, owing to population aging. Hip and vertebral fractures are associated with increased mortality and morbidity. Costs related to fragility fractures represent a significant burden for health care systems. L'ostéoporose est à l'origine de fractures par frag... Med Worm[the challenges of the bone micro-architecture.] [The challenges of the bone micro-architecture.] J Soc Biol. 2008;202(4):265-73 Authors: Rachidi M, Breban S, Benhamou CL Osteoporosis is a bone disorder that leads to increased fracture risk. It was defined by the World Health Organisation as a decrease of bone mass and a deterioration of bone quality. In clinical practice, the diagnosis of osteoporosis is based on bone mineral density (BMD) measurements assessed by dual energy X-ray absorptiometry. However, BMD assessment is not the only factor that influences bone strength. The main objective is that clinicians can use a combination of risk factors that are easily assessable, for a better prediction of osteoporosis risk fracture. Bone strength reflects both bone density and bone quality. One of the most important determinant... Med WormVulnerability To Post-Traumatic Stress Disorder Runs In Families Earthquakes have aftershocks - not just the geological kind but the mental kind as well. Just like veterans of war, earthquake survivors can experience post-traumatic stress disorder, depression and anxiety.In 1988, a massive earthquake in Armenia killed 17,000 people and destroyed nearly half the town of Gumri. Now, in the first multigenerational study of its kind, UCLA researchers studying survivors of that catastrophe have discovered that vulnerability to PTSD, anxiety and depression runs in families.read more Emax healthSiblings Of Mentally Disabled Face Challenges People who have a sibling with a mental illness are more likely to suffer episodes of depression at some point in their lives, say researchers who analyzed four decades of data.Additionally, they found people with a sibling with low IQ are more likely to live near that brother or sister - but be somewhat emotionally detached from that sibling.The findings were reported in the December issue of the Journal of Family Psychology, published by the American Psychological Association.read more Emax healthStructure and dynamics of the n-terminal half of hepatitis c virus core protein: an intrinsically unstructured protein. Structure and dynamics of the N-terminal half of hepatitis C virus core protein: an intrinsically unstructured protein. Biochem Biophys Res Commun. 2009 Jan 2;378(1):27-31 Authors: Duvignaud JB, Savard C, Fromentin R, Majeau N, Leclerc D, Gagné SM Hepatitis C virus core protein plays an important role in the assembly and packaging of the viral genome. We have studied the structure of the N-terminal half of the core protein (C82) which was shown to be sufficient for the formation of nucleocapsid-like particle (NLP) in vitro and in yeast. Structural bioinformatics analysis of C82 suggests that it is mostly unstructured. Circular dichroism and structural NMR data indicate that C82 lacks secondary structure. Moreover, NMR relaxation data shows that C82 is highly disordered. Th... medworm.comBulimia patient given chance to correct her eating disorder Singapore - A Singapore Community Court has postponed jail sentencing on a 48-year old woman who suffers from the eating disorder bulimia, reported the Straits Times Saturday. Yeow Cheng Chiam, who had been convicted of food theft nine times since 19... EarthTimes.orgColon cancer gap widens between blacks, whites ATLANTA -- The racial gap in colon cancer death rates is widening, a new report says, and experts partly blame blacks' lower screening rates and poor access to high quality care. TelegrapheSusceptibility to PTSD, depression and anxiety may be inherited Washington, December 20 : A study on the survivors of the massive 1988 earthquake that killed 17,000 people in Armenia, and destroyed nearly half the town of Gumri, has revealed that vulnerability to post-traumatic stress disorder, depression and anxiety may be inherited through genes. bignewsnetwork.comJanssen-Cilag International N.V. Withdraws Its Application For An Extension Of Indication For Invega (paliperidone) The European Medicines Agency (EMEA) has been formally notified by Janssen-Cilag International N.V. of its decision to withdraw its application for an extension of indication for the centrally authorized medicine Invega (paliperidone) prolonged-release tablets. Invega was expected to be used for the treatment of acute manic episodes associated with bipolar I disorder. Invega was first authorised in the European Union on 25 June 2007. Medicalnewstoday.com1 2 |
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