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Study may predict if hepatitis C drugs will work
CHICAGO (Reuters) - Doctors hope to be able to better predict which patients will respond to traditional treatment for the hepatitis C virus using a new method for identifying slight variances in the virus' genetic makeup.
Reuters

The hydrophobic motif of rock2 requires association with the n-terminal extension for kinase activity
ROCK2 is a member of the AGC kinase family that plays an essential role downstream of Rho in actin-cytoskeleton assembly and contractility. The process of ROCK2 activation is complex and requires suppression of an auto-inhibitory mechanism that is facilitated by Rho binding. ROCK2 harbors a C-terminal extension within the kinase domain that contains a hydrophobic cluster of phenylalanine and tyrosine residues surrounding a key threonine. In growth-factor stimulated AGC kinases the hydrophobic motif is important for the transition of the kinase from inactive to active complex and requires phosphorylation of the conserved serine/threonine residue. Less is understood about the contribution that the hydrophobic motif plays in the activation of ROCK, and the role of the hydrophobic motif threon...
medworm.com

Drinkers with the ADH1C gene at greater risk of colorectal cancer
Chronic drinking is a risk factor for colorectal cancer, possibly through the effects of acetaldehyde, which is created by the alcohol dehydrogenase (ADH) enzyme.
news-medical.net

Researchers Find Evidence About Evolution Of HIV In Lemurs
Researchers at the Stanford University School of Medicine have discovered a virus related to HIV in the genetic makeup of the Madagascar grey mouse lemur, a finding that could provide new evidence about the origins of HIV, according to a study recently published in the Proceedings of the National Academy of Sciences,
Medical News Today

Eggs Contribute Insignificant Risk To Heart Disease
A study recently published online in the journal Risk Analysis(1) estimates that eating one egg per day is responsible for less than 1 percent of the risk of coronary heart disease (CHD) in healthy adults. Alternatively, lifestyle factors including poor diet, smoking, obesity and physical inactivity contribute 30 to 40 percent of heart disease risk, depending on gender.
Medical News Today

Simple model predicts those at risk for chronic kidney disease
(New York- Presbyterian Hospital/Weill cornell medical Center/Weill Cornell Medical College) Traditionally, doctors have had no clear way to predict which of their patients might be headed down the road to chronic kidney disease. Now, researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center and the University of North Carolina at Chapel Hill have created a simple eight-point risk factor checklist to do just that.
Eurekalert.org

MU professor recommends changing drivers` perceptions of law enforcement to deter drunk driving
(University of Missouri-Columbia) In 2007, approximately 1,500 people nationwide were killed in crashes that involved a drunk driver from Thanksgiving through New Year's Day. Researchers from the University of Missouri and the University of Georgia found that the most important deterrence factors for high-risk drivers are their perceptions of the likelihood of being stopped or arrested and their support for deterrence laws.
Eurekalert.org

Recreating A Nerve Disease In Order To Study It - Patient-derived Induced Stem Cells Retain Disease Traits
Clive Svendsen, of the University of Wisconsin-Madison, could not have been happier when neurons started dying in his lab dishes. Clive and team had created the hallmarks of a genetic disorder in the laboratory using stem cells derived from a patient. The dying cells were the same type lost in patients with spinal muscular atrophy, a devastating neurological disorder. In other words, a gene disease had been recreated in the lab by scientists.
Medicalnewstoday.com

Gene disease `recreated in lab`
Scientists say they can watch genetic diseases unfolding in the laboratory after finding a way to reproduce affected cells.
BBC

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Archived "health - genetic factors" news stories.

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