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Opposition MP in Malaysia `withdraws HIV remarks` (AFP)
A senior opposition politician withdrew his statement that people with HIV should be banned from marriage, after he was criticised by AIDS activists, a report said Sunday.
yahoo.com

News From The Journals Of The American Society For Microbiology
Killer Peptide May Offer New Therapy Against Influenza A Virus In a new study researchers identified what appears to be the first antibody-derived peptide that inhibits the activities of harmful microbes such as influenza A virus and HIV-1. They report their findings in the December 2008 issue of the journal Antimicrobial Agents and Chemotherapy.
Medicalnewstoday.com

Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype
IntroductionDespite intense studies on the mechanisms of chemotherapeutic drug resistance in human breast cancer, few reports have systematically investigated mechanisms underlying resistance to the chemotherapy-sensitizing agent, tumor necrosis factor-alpha (TNF-alpha). Additionally, the relationship between TNF-alpha resistance mediated by MEK5/Erk5 signaling and epithelial-mesenchymal transition (EMT), a process associated with promotion of invasion, metastasis, and recurrence in breast cancer, has not been previously investigated. Methods:To compare differences in the proteome of the TNF-alpha resistant MCF-7 breast cancer cell line MCF-7-MEK5, mediated by MEK5/Erk5 signaling, and its parental TNF-alpha sensitive MCF-7 cell line MCF-7-VEC, two dimensional gel electrophoresis and high performance capillary liquid chromatography coupled to tandem mass spectrometry approaches were used. Differential protein expression was verified at the transcriptional level using RT-PCR assays. A
MedicineNet

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