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Single Letter In Human Genome Points To Risk For High Cholesterol Write out every letter in the human genome, one A, C, T or G per millimeter, and the text would be 1,800 miles long, roughly the distance from New York to Colorado. Now, in the search for genes that affect how humans synthesize, process and break down cholesterol, scientists have found a single letter among this expanse of code that is associated with elevated LDL cholesterol levels, one of the leading health concerns that has come to dominate the 21st century. Science DailyTNF-alpha Blockers The first TNF-alpha blocker, Enbrel, was marketed in 1998. A decade later, we're learning more about how well the drugs work and side effects associated with them. TNF-alpha blockers are very effective for some but they are not for everyone. AboutRegulation of matrix metalloproteinase-9 expression between gingival fibroblast cells from old and young rats. Authors: Kim SJ, Chung YK, Chung TW, Kim JR, Moon SK, Kim CH, Park YG Gingival fibroblast cells (rGF) from aged rats have an age-related decline in proliferative capacity compared with young rats. We investigated G1 phase cell cycle regulation and MMP-9 expression in both young and aged rGF. G1 cell cycle protein levels and activity were significantly reduced in response to interleukin-1beta (IL-1beta) stimulation with increasing in vitro age. Tumor necrosis factor-alpha (TNF-alpha)-induced matrix metalloproteinase-9 (MMP-9) expression was also decreased in aged rGF in comparison with young rGF. Mutational analysis and gel shift assays demonstrated that the lower MMP-9 expression in aged rGF is associated with lower activities of transcription factors NF-kappaB and AP-1. These results ... medworm.comUnderstanding Emotional Eating Emotional eating is a common way for us to avoid emotions, and many of us don't realize we're doing it. But emotional eating doesn't have to have control of your life. AboutScientists Identify New Congenital Neutropenia Syndrome, Causative Gene Mutation A team of scientists has discovered a new syndrome associated with severe congenital neutropenia (SCN), a rare disorder in which children lack sufficient infection-fighting white cells, and identified the genetic cause of the syndrome: mutations in the gene Glucose-6-phosphatase, catalytic subunit 3 (G6PC3). The findings, which are published in the Jan.read more emaxhealth.comFlu Season Is Here: How To Detect Symptoms Of Viral Myocarditis In Children And Young Adults Influenza, strep throat and the common cold afflict many people during the winter months, particularly in children and young adults, yet there is one often undiagnosed viral condition that can be far deadlier then these common viruses. Viral myocarditis is a sometimes fatal infection that inflames the myocardium, the thick muscular layer of the heart wall, and is the most common cause of heart failure in otherwise healthy children and young adults. MedicineNet |
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9th of September 2009 - Interview of Feedzilla's founder at the IFA in Berlin. [More]
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