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Pain Scales Help Arthritis Patients Rate Their Level of Pain
Pain scales help arthritis patients rate their level of pain so it can be communicated to their doctor, other health professionals, or even family. It's a self-reported pain level so...
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Fractional Exhaled Nitric Oxide Doesn`t Seem To Benefit Children With Asthma
The level of nitric oxide (NO) in an asthmatic's exhaled breath can portend worsening asthma symptoms, and may even signify an imminent attack linked to underlying airway inflammation.
Med India

Production of nitric oxide and expression of inducible nitric oxide synthase in ovarian cystic tumors
Tumor sections from nonneoplastic (n=15), benign (n=28), and malignant ovarian tumors (n=20) were obtained from 63 women. Immunohistochemistry of the tumor sections demonstrated that inducible nitric oxide synthase (iNOS) expression was increased in ovarian cancer samples compared to nonneoplastic or benign tumor samples. Using the Griess method, nitric oxide (NO) metabolite levels were also found to be elevated in malignant tumor samples compared to benign tumor samples (P<.05). For stage I ovarian cancer, intracystic NO levels >80 μM were more frequent than NO levels <80 μM, and iNOS expression in well-differentiated carcinomas was greater than in moderately/poorly differentiated carcinomas (P<.05). These data suggest an important r... MedWorm Message: Find out how you can get your message across here by sponsoring this MedWorm news feed.
medworm.com

Cardio Coach Volume 2
The Cardio Coach Volume 2 CD is an excellent choice for anyone who wants to revive their cardio workouts. It offers a guided interval workout on any machine of your choice for all levels of fitness.
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Lifelong Gender Difference In Physical Activity Revealed By Studies
Females of all ages are less active than their male peers. Two studies, presented today (Tuesday 6 January) at a major academic conference, reveal the gender difference in activity levels among school children and the over 70s. Both studies show males to be more physically active than females.
Medicalnewstoday.com

PI3K targeting by the beta-GBP cytokine negates akt gene expression and leads aggressive breast cancer cells to apoptotic death
IntroductionPI3K activated signaling has a critical role in the evolution of aggressive tumorigenesis and is therefore a prime target for anti-cancer therapy. In previous work we have shown that the beta galactoside binding protein (betaGBP) cytokine, an anti-proliferative molecule, induces functional inhibition of class 1A and class 1B PI3K. Here we have investigated whether, by targeting PI3K, betaGBP has therapeutic efficacy in aggressive breast cancer cells where strong mitogenic input is fuelled by overexpression of the ErbB2 oncoprotein receptor and have used as controls immortalised ductal cells and non aggressive mammary cancer cells, which express ErbB2 at low levels.Methods:Cells used: aggressive BT474 and SKBR3 cancer cells where ErbB2 is overexpressed; MCF10A immortalised ductal cells and non-invasive MCF-7 cancer cells which express low levels of ErbB2, both in their naive state and when forced to mimic aggressive behaviour. Class IA PI3K was immunoprecipitated and the c
breast-cancer-research.com

Goal-Setting Drills Make For More Active Coworkers
Workplace programs that encourage employees to set exercise goals pay off, finds a new study that looked at physical activity levels of Home Depot employees who participated in the 'Move to Improve' program. The program increased the proportion of employees who regularly participated in either moderate or vigorous physical activity from about 30 percent at the start of the study to about 50 percent during the last six weeks, said lead author Rod Dishman, Ph.D.
Medicalnewstoday.com

UCB Receives Complete Response Letter From U.S. FDA For Use Of Cimzia® In Rheumatoid Arthritis Patients
UCB announced today that the US Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) relating to the Biologics License Application (BLA) of Cimzia® (certolizumab pegol), the first PEGylated anti-TNF, for the treatment of rheumatoid arthritis (RA). As a prerequisite for approval of Cimzia®, the FDA has requested a new safety update with all clinical data including new data generated since the filing of the BLA.
Jointogether.org

Stress hormone `a marker for ME`
Low levels of the stress hormone cortisol in children linked to higher risk of chronic fatigue syndrome as adults.
BBC

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9th of September 2009 - Interview of Feedzilla's founder at the IFA in Berlin. [More]

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