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`Nonsense` In Our Genes: One In 200 Human Genes Superfluous? A study of the genetic code of more than 1,000 people has found that at least one in 200 human genes can be inactivated in apparently healthy people. The findings suggest that, though these genetic mutations can be harmful, they generally have little effect on the individual and could occasionally even be beneficial in evolutionary terms. The study also found that individuals carry on average 46 of these inactivating mutations. Science DailyCognitive Impairment Associated With Heart Failure Nearly half of patients with heart failure (HF) have problems with memory and other aspects of cognitive functioning, reports a new study.Memory problems and other cognitive deficits may be an important factor to consider in planning medical care for patients with HF, says researcher Mary Jane Sauvé, D.N.Sc., R.N., of the University of California, Davis.The [...] PsychcentralAdult Stem Cells Convert Into Embryonic-like Stem Cells, With Single Factor The simple recipe scientists earlier discovered for making adult stem cells behave like embryonic-like stem cells just got even simpler. A new report shows for the first time that neural stem cells taken from adult mice can take on the characteristics of embryonic stem cells with the addition of a single transcription factor. Transcription factors are genes that control the activity of other genes. Science DailyMany unaware of the link between weight, smoking, and cancer A "shocking" number of people don't know that being overweight is a main risk factor for cancer, a new survey has found. Health CentralMental retardation linked with gene mutation A genetic mutation may contribute to nonsyndromic mental retardation, the most common form of mental retardation suffered by children, a new study has found. What's unusual about the mutation is that... bignewsnetwork.comNews Scan Briefs: Weak on the Nano Risk Amnio Alternative Amniocentesis and other prenatal tests designed to assess fetal health carry a small risk of miscarriage. Now Chinese researchers may have found an alternative diagnostic method based on a technique that distinguishes maternal DNA from fetal DNA in the mother’s blood. That ability could lead to simple, no-risk blood tests that determine whether a fetus has a problem caused by single-gene mutations, such as cystic fibrosis and sickle cell anemia. The fetal DNA, which tends to be shorter than that of the mother, is duplicated and subjected to a “molecular counting” technique that tallies both mutant and normal genetic material. Researchers can use the data to determine whether the fetus has inherited a monogenetic disease. The San Diego–based biotech company Sequenom plans to develop the test for commercial distribution. The study appears in the December 16, 2008, Proceedings of the National Academy of Sciences USA. --Gary Stix [More] Scientific AmericanIdentifying Experimental Drug For Rare Genetic Diseases A study by National Institutes of Health (NIH) researchers has revealed surprising new insights into the process used to initially identify an experimental drug now being tested in people with cystic fibrosis and muscular dystrophy. Researchers emphasized the clinical implications of their findings are unclear, but said the results suggest more work may be needed to make sure the screening process to select promising agents was not flawed by its effects on a firefly enzyme used as a marker. The study was published today in the Proceedings of the National Academy of Sciences (PNAS).read more eMaxHealthGenetic Adaptations Are Key To Microbe`s Survival In Challenging Environment The genome of a marine bacterium living 2,500 meters below the ocean's surface is providing clues to how life adapts in extreme thermal and chemical gradients, according to an article published February 6 in the open-access journal PLoS Genetics. The research focused on the bacterium Nautilia profundicola, a microbe that survives near deep-sea hydrothermal vents. Medical News TodayLink Between Heart Failure And Cognitive Impairment Nearly half of patients with heart failure (HF) have problems with memory and other aspects of cognitive functioning, reports a new study published by Elsevier, in the February issue of Journal of Cardiac Failure. Memory problems and other cognitive deficits may be an important factor to consider in planning medical care for patients with HF, according to the new study, led by Mary Jane SauvĂ©, D.N.Sc., R.N., of the University of California, Davis. Medical News TodayScientists Propose New Direction In The Search For Genetic Causes Of Schizophrenia A new study shows that schizophrenia is caused, at least in part, by large, rare structural changes in DNA referred to as copy number variants (CNVs) - not the tiny, single letter alterations (single nucleotide polymorphisms (SNPs) that scientists have pursued for years. The findings are published February 6 in the open-access journal PLoS Genetics. Medicalnewstoday.com1 2 |
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