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Atopic dermatitis (AD) is an inflammatory skin disease in which pathogenesis chemokines are partially involved. The aim of the paper was to assess the serum level of CXCL-9, CXCL-10, CXCL-11, CXCL-12, CCL-17, CCL-20, CCL-21, CCL-22, CCL-27, and IL-18 chosen in AD patients by ELISA assay. Forty patients (mean age 11.4 years old) with AD and 50 healthy controls were enrolled into the study. The patients and controls were divided into two age categories: under 10 years old (Group 1 and Control 1) and over 10 years old (Group 2 and Control 2). Significantly lower serum concentration of CXCL-9, CXCL-10, CCL-17, and IL-18 and higher concentration of CXCL-12 and CCL-27 were found in Group 1 whe...MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources.

Singapore - Singapore on Wednesday reported two more fatalities related to H1N1 influenza. A 13-year-old boy suffering from epilepsy died of a prolonged epileptic seizure with influenza H1N1 infection as a contributing factor, the Health Ministry sai...

The translocation of folded proteins via the twin-arginine translocation (Tat) pathway is regulated to prevent the futile export of inactive substrate. DmsD is part of a class of cytoplasmic chaperones that play a role in preventing certain redox proteins from premature transport. DmsD from Escherichia coli has been crystallized in space group P41212, with unit-cell parameters a = b = 97.45, c = 210.04 Å, in the presence of a small peptide. The structure has been solved by molecular replacement to a resolution of 2.4 Å and refined to an R factor of 19.4%. There are four molecules in the asymmetric unit that may mimic a higher order structure in vivo. There appears to be density for the peptide in a predicted binding pocket, which lends support to its role as the signal-recognition ...

Understanding asthma causes and asthma risks can help prepare you for the development of asthma. The causes of asthma are diverse, but experts do know what many asthma risk factors are.

At the neighborhood level, socioeconomic and demographic factors are the strongest predictors of high obesity rates, experts argue.

In Health Watch: roughly a third of adults in the U.S. have high blood pressureNow, a new study shows by changing your behaviors six ways, your hypertension risk can be significantly reduced.Haley Weldon has more.High blood pressure - or hypertension - is a major contributing factor to the leading causes of death for men and women in the U.S.Dr.

ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company (NYSE: LLY), and Bristol-Myers Squibb Company (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) has approved revisions to the U.S. prescribing information for ERBITUX® (cetuximab) concerning the treatment of patients with epidermal growth factor receptor (EGFR)-expressing metastatic colorectal cancer (mCRC).

(Johns Hopkins Medical Institutions) A study led by Johns Hopkins and Utah State University researchers suggests that a particularly close relationship with caregivers may give people with Alzheimer's disease a marked edge over those without one in retaining mind and brain function over time. The beneficial effect of emotional intimacy that the researchers saw among participants was on par with some drugs used to treat the disease.

Citing an argument used by the Bush administration, the Secret Service rejects a request from a watchdog group to list those who have visited the White House to discuss the healthcare overhaul. Invoking an argument used by President George W. Bush, the Obama administration has turned down a request from a watchdog group for a list of health industry executives who have visited the White House to discuss the massive healthcare overhaul.

Researchers have found that statins can normalize vascular lysyl oxidase (LOX) expression modified by atherogenic risk factors.