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Interleukin-6 maintains bone marrow-derived mesenchymal stem cell stemness by an ERK1/2-dependent mechanism In this study, we showed that IL-6 gene expression is significantly higher in undifferentiated MSCs as compared to their chondrogenic, osteogenic, and adipogenic derivatives. Moreover, we found that MSCs secrete copious amounts of IL-6 protein, which decreases dramatically during osteogenic differentiation. We further evaluated the role of IL-6 for maintenance of MSC 'stemness,' using a series of functional assays. The data showed that IL-6 is both necessary and sufficient for enhanced MSC proliferation, protects MSCs from apoptosis, inhibits adipogenic and chondrogenic differentiation of MSCs, and increases the rate of in vitro wound healing of MSCs. We further identified ERK1/2 activation as the key pathway through which IL-6 regulates both MSC proliferation and inhibition of differentia...MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources. Med WormStudy Finds Estrogen Receptor-Negative Tumors Have Vaccine Targets Main Category: Breast Cancer Also Included In: Genetics ; Immune System / Vaccines ; Clinical Trials / Drug Trials Article Date: 28 Jul 2009 - 3:00 PDT A comprehensive analysis of nearly 1,600 tumor samples has found that CT-X genes are expressed in nearly half the breast cancers that lack the estrogen receptor . MedicineNetSurgery May Relieve Migraines, Study Shows Nearly one out of every six Americans suffers from migraine headaches. Research has shown that one cause for the painful headaches is irritation in certain nerves in the face. Topix.netVideo: A Model For Health Reform With the debate over health care reform raging in Washington, many who study the issue are looking closely at one state that has already tackled reform on a comprehensive. Priya David reports. CBS NewsMutation Responsible For Cystic Fibrosis Also Involved In Muscle Atrophy Patients with cystic fibrosis usually experience significant muscle loss, a symptom traditionally considered to be a secondary complication of the devastating genetic disease. However, a recent study reverses the equation: new results show that muscle atrophy and weakness may be a primary symptom caused by the effects of CFTR gene mutations on the muscle itself. sciencedaily.comAmericans spend $34B for alternative medicine ATLANTA (AP) -- Americans spend more than a 10th of their out-of-pocket health care dollars on alternative medicine, according to the first national estimate of such spending in more than a decade.... Associate PressDrug Court Comes to Mexico ONDCP Director Gil Kerlikowske joins NADCP faculty and CEO West Huddleston for a planning session with a delegation from Mexico at NADCP's 15th Annual Training Conference Photo (c) National Association of... AboutMany physicians believe nothing can be done to alter course of dementia: study Two years ago, Stuart Brandy would be reading a book or trying to get some paperwork done when suddenly he would have no idea what he was doing. Topix.netCan Green Tea Help Prevent Cancer? A recent review of green tea's cancer-preventing properties has yielded mixed results. For the review, scientists sized up 51 studies (including a total of more than 1.6 million participants) on the... about.comSubjective symptoms of sleep quality and daytime sleepiness associated with declining quality of life A study in the Aug. 1 issue of the journal Sleep indicates that self-reported worsening in initiating and maintaining sleep over a five-year period was significantly associated with poorer mental quality of life, and increasing daytime sleepiness symptoms were associated with both poorer physical and mental quality of life. Topix.net1 2 3 4 |
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How does Feedzilla work?
Feedzilla is a news aggregator which categorizes news stories by topic. It is a platform where webmasters and bloggers can find an unmatched selection of easy to use, automatically updating and professional news widgets for their sites. Feedzilla supports the building of widgets in various formats, as well as allowing the addition of news widgets to different blogging platforms and social networks.
Feedzilla manually aggregates news summaries found in RSS feeds, and redistributes them in either RSS format or as a news widget. Content is collected 24 hours a day, 7 days a week from an ever-growing list of providers.
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9th of September 2009 - Interview of Feedzilla's founder at the IFA in Berlin. [More]
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The news feeds I added to my websites made them much more interesting! Thanks a lot!
Lionel Gibbons
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