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High-dose Therapy For Liver Disease Not Effective, Study Suggests
Scientists have found that a common treatment for primary sclerosing cholangitis, a chronic liver disease, is not helpful for patients.
sciencedaily.com

Breast cancer intervention reduces depression, inflammation
A psychological intervention for newly diagnosed breast cancer patients with symptoms of depression not only relieves patients' depression but also lowers indicators of inflammation in the blood.
Topix.net

Breast Cancer Intervention Reduces Depression and Inflammation
Posted on: Monday, 31 August 2009, 16:55 CDT A psychological intervention for newly diagnosed breast cancer patients with symptoms of depression not only relieves patients' depression but also lo...
bignewsnetwork.com

When HER2 is not the target: advances in the treatment of HER2-negative metastatic breast cancer
The anti-HER2 agent trastuzumab has improved outcomes for breast cancer patients with HER2-overexpressing tumours. However, systemic treatment for patients with HER2-negative disease is still limited to endocrine and cytotoxic therapies. The increasing use of the anthracyclines and taxanes in early stage disease has reduced the available therapeutic options for patients with relapsed disease, and options are further limited for patients with triple-negative tumours, who typically have a poor prognosis. The novel agents bevacizumab and ixabepilone have recently been approved for metastatic breast cancer and numerous other agents are currently in clinical development that may contribute further valuable therapeutic options.
breast-cancer-research.com

Recent Advances in Systemic Therapy for Breast Cancer: New technologies for a new Era
The last decade has brought enormous advance in the way we manage breast cancer patients with systemic therapies. An explosion in our understanding of the molecular pathogenesis of breast cancer, a harnessing of powerful new diagnostic technologies, and the culmination of a series of pivotal randomised trials of cytotoxic and novel targeted therapies has seen significant improvements in outcome for patients with both early and advanced disease. This series of articles by leading clinical researchers explore these advances in different areas of breast cancer management.
breast-cancer-research.com

ESC: Green Light for PPIs Plus Antiplatelet Drugs (CME/CE, with video)
BARCELONA (MedPage Today) -- Patients who have a proton pump inhibitor and a thienopyridine on board when they undergo stenting will not receive the full effect of the antiplatelet drug, but their risk of myocardial infarction, stroke, or death does not appear any higher.
Med Page Today

Few Studies Support Drug Combos for Cutting Cholesterol (CME/CE)
High-dose statin monotherapy generally reduces cholesterol as well as combining a statin with another drug, although there is some evidence that a statin combined with ezetimibe in high-risk patients is slightly more effective than statins alone, a systematic review has shown.
Med Page Today

Routine Warfarin Use for Afib Questioned (CME/CE)
Warfarin therapy for atrial fibrillation is most beneficial for older patients and those at high risk of stroke, according to the findings of a large, new study that provides evidence that doctors should carefully weigh the benefits and risks of warfarin for other patients.
Med Page Today

Mediterranean Diet Reduces Need for Diabetes Drugs (CME/CE)
The so-called Mediterranean diet (MedPage Today) -- rich in nuts, whole grains, fruits, and vegetables -- reduces the likelihood that patients recently diagnosed with type 2 diabetes will need antihyperglycemic drug treatment, a new study found.
Med Page Today

New Tool To Predict Risk Of Death In COPD May Help Physicians To Individualize Treatment
Researchers have developed an index scale to help physicians predict a patient's risk of dying from chronic obstructive pulmonary disease (COPD). The ADO index can help physicians assess the severity of a patient's illness to determine the appropriate level of treatment. COPD is a major public health problem and it is the fourth leading cause of death in the US.
Science daily

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November 2009
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