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Idera Pharmaceuticals Initiates Phase 1 Clinical Trial Of IMO-2125, A ... Main Category: Liver Disease / Hepatitis Also Included In: Clinical Trials / Drug Trials Article Date: 09 Oct 2009 Idera Pharmaceuticals, Inc. Topix.netNIH Prepares to Launch 2009 H1N1 Influenza Vaccine Trial in People with Asthma The National Institutes of Health is preparing to launch the first government-sponsored clinical trial to determine what dose of the 2009 H1N1 influenza vaccine is needed to induce a protective immune response in people with asthma, especially those with severe disease. The study is cosponsored by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Heart, Lung, and Blood Institute (NHLBI), both part of NIH. National Institutes of HealthLpath`s ISONEP Is Well Tolerated At All Dose Levels In A Phase 1 Trial In Wet-AMD Patients Lpath, Inc. (OTCBB: LPTN), the category leader in lipidomics-based therapeutics, reported positive summary results of its single-dose Phase 1 clinical trial of iSONEP(TM) in wet-AMD patients. iSONEP met its primary endpoint of being well tolerated in all 15 patients at dose-levels ranging from 0.2 mg. to 1.8 mg. per intravitreal injection (three patients per dose level). No drug-related serious adverse events were reported in any of the patients. Medical News TodayEADV: TNF Inhibitor Active in Palmoplantar Psoriasis (CME/CE) BERLIN (MedPage Today) -- Patients with palmoplantar psoriasis had at least 50% improvement after 14 weeks when treated with a tumor necrosis factor (TNF) inhibitor, according to results of a small clinical trial reported here. Med Page TodayMuscular Dystrophy Association Applauds New Federal Support For Neuromuscular Diseases The National Institutes of Health has announced a $117 million expansion of its Rare Diseases Clinical Research Network, adding 14 research consortia, or groups, to the Network's second phase and will continue funding the five original groups. Having long recognized the research challenges for communities affected by rare disorders, the National Institutes of Health established the Office of Rare Disease Research in 1993 to ensure an increased focus on rare disorder treatment discovery. Medical News TodayIs Depression After an Acute Coronary Syndrome Simply a Marker of Known Prognostic Factors for Mortality? Objective: Controversy remains over whether the association between depression and mortality in patients with acute coronary syndrome (ACS) is confounded by incomplete adjustment for measures of known prognostic markers. We assessed a) whether depression was associated with the most comprehensive empirically derived index of clinical mortality predictors: the Global Registry of Acute Coronary Events (GRACE) risk score for predicting 6-month mortality after discharge for ACS; and b) whether depression remained an independent predictor of all-cause mortality after adjustment for the GRACE score and left ventricular dysfunction. Methods: We surveyed prospectively 457 patients with ACS (aged 25–92 years; 41% women, 13% black, and 11% Hispanic), hospitalized between May 2003 and June 2005. Depressive symptoms were assessed with the Beck Depression Inventory (BDI) and diagnosis of major depressive disorder (MDD) was made by a structured psychiatric interview, within 1 week of hospit psychosomaticmedicine.orgEADV: Scalp, Nail Psoriasis Improve with TNF Inhibitor (CME/CE) BERLIN (MedPage Today) -- Treatment with a tumor necrosis factor (TNF) inhibitor significantly improved scalp and nail psoriasis as well as skin lesions, according to a retrospective analysis of a randomized clinical trial. Med Page TodayBone mineral density and fractures in older men with chronic obstructive pulmonary disease or asthma Conclusion Chronic obstructive pulmonary disease or asthma was associated with lower BMD at the spine and hip and increased risk of vertebral and nonvertebral fractures independent of age, clinic site, BMI, and smoking. A history of COPD or asthma may be a useful clinical risk factor to identify patients with osteoporosis. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1076-xAuthors T.-T. Dam, Columbia University Department of Medicine, College of Physicians and Surgeons New York New York USAS. Harrison, Research Institute, California Pacific Medical Center San Francisco California USAH. A. Fink, University of Minnesota Geriatric Research Education and Clinical Center and Center for Chronic Disease Outcomes Research, Veterans Affairs Medic...MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources. Med WormSymposium On Cardiovascular Regenerative Medicine Oct. 14 -15 With advancements in the field of stem cell research accelerating, the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) will hold its third Symposium on Cardiovascular Regenerative Medicine to review the latest findings in the field and examine future directions. The symposium will include a discussion on ways to move promising findings in the laboratory into clinical trials, in hopes of speeding stem cell-related treatments to patients. Medical News TodayBreast-Specific Gamma Imaging Proves Cost-Effective For Pre-Surgical Planning Of Patients With Known Cancer Diagnosis Breast-Specific Gamma Imaging (BSGI), a molecular breast imaging technique with comparable sensitivity to breast magnetic resonance imaging (MRI) for detecting breast carcinoma when used in pre-surgical planning for patients with known cancer diagnoses and is substantially less expensive than MRI, according to findings presented at the American Society of Clinical Oncology Breast Cancer Symposium in San Francisco, California. Medical News Today1 2 3 |
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