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Glaxo told to pay $2.5 million in case linking Paxil, birth defects
GlaxoSmithKline PLC must pay $2.5 million to settle a claim that its antidepressant Paxil caused severe heart defects in a 3-year-old boy, a Philadelphia jury found Wednesday.
Topix.net

Pink Ribbon Crafting For The Cure Supports Survivors
Pink Ribbon PumpkinPhoto ©Kellie Walenciak Are you big on heart - but low on cash? Have time, materials and some creativity? Then you can make a gift to support...
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Residents Of Minn. Town Add 3.1 Years To Lives
Hardware store owner and heart attack survivor Leo Aeikens spent most of his life with a hankering for meat, cheese and ice cream. But an ambitious effort aimed at making his entire southern Minnesota town healthier has Aeikens calling himself a vegan and weighing 25 pounds less than just 10 months ago.
cbs2chicago.com

SAfrica to limit trans fats as heart disease rises
JOHANNESBURG (AP) -- South Africa's health department says it will draft regulations aimed at reducing the trans fats South Africans consume....
The Arizona Republic

Faulty gene may explain sudden deaths in epilepsy
CHICAGO (Reuters) - A common gene that can cause abnormal heart rhythms can also trigger epileptic seizures in the brain and may explain the sudden, unexplained deaths that often occur in people with epilepsy, U.S. researchers said on Wednesday.
Reuters

Minnesota town gets healthy together
Hardware store owner and heart attack survivor Leo Aeikens spent most of his life hankering for meat, cheese and ice cream. But ...
USATODAY

Can fish for dinner lead to diabetes?
New york (Reuters Health) - Making sure fish ends up on your dinner plate a couple of times a week may be a good way to cut your risk for developing heart disease, but it may not do the same for diabetes, new study findings hint.
Reuters

Suppressing A Gene In Mice Prevents Heart From Aging, Preserves Its Function
In a mouse study, suppressing the activity of a key gene prevented age-related cardiac changes and preserved much of the heart's function. The study provides more evidence that physicians may one day prevent age-related heart failure in humans.
Science Daily

Autonomy of Autonomic Dysfunction in Major Depression
Objective: To investigate cardiac autonomic dysfunction in patients with major depressive disorder (MDD). Research in this area has faced several limitations because of the heterogeneity of the disease, the influence of medication, and methodological shortcomings. Methods: Participants were 75 patients suffering from an acute recurrent episode of MDD and 75 matched controls. All participants were assessed at baseline for linear and nonlinear parameters of heart rate variability, QT variability and baroreflex sensitivity. Participants with MDD were reassessed after 7 to 9 days of treatment with either a selective serotonin reuptake inhibitor (SSRI) or a serotonin and noradrenaline selective reuptake inhibitor (SNRI) antidepressant. Results: In the initial examination, patients showed an overall shift of autonomic balance toward sympathetic predominance as compared with matched controls, with a decrease in parasympathetic parameters and baroreflex sensitivity, and an increase in symp
psychosomaticmedicine.org

Association Between Symptoms of Depression and Anxiety With Heart Rate Variability in Patients With Implantable Cardioverter Defibrillators
Objective: This study investigated whether depression and anxiety symptoms are associated with measures of autonomic nervous system dysfunction in patients with implantable cardioverter defibrillators who are at high risk of cardiac rhythm disturbances. Depression and anxiety are associated with autonomic nervous system dysfunction, which may promote the risk of malignant cardiac arrhythmias. Methods: Patients with an implantable cardioverter defibrillator (ICD) underwent ambulatory electrocardiographic (ECG) monitoring (n = 44, mean age = 62.1 ± 9.3 years). Depression was assessed using the Beck Depression Inventory and anxiety was evaluated using the Taylor Manifest Anxiety Scale. Heart rate variability was assessed using time (RMSSD, pNN50, and SDNN) and frequency domain measures derived from 24-hour R-R intervals. Multivariate models were adjusted for age, sex, hypertension, diabetes, and smoking status. Results: Defibrillator patients with elevated depression symptoms (
psychosomaticmedicine.org

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