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Celsion And Yakult Honsha Announce Treatment Of First Patient In Japan In Celsion`s Global Phase III ThermoDox(R) Trial For Primary Liver Cancer
Celsion Corporation (NASDAQ: CLSN) and Yakult Honsha Co., Ltd. (Tokyo: 2267) announced today that the first patient has been enrolled and treated in Japan as part of Celsion's global Phase III ThermoDox HEAT trial for the treatment of hepatocellular carcinoma (HCC), the most common form of primary liver cancer.
Medical News Today

Testicular Cancer Survivors Face Other Ills
Treatment can cause long-term neurological, circulatory problems, study finds
Forbes

Patients with chronic diseases to be screened for depression
Patients sufferring from serious diseases like cancer or heart disease should be screened for depression, new NHS guidance has recommended Men and women with long-term health problems are known to be two or three times more likely to be depressed than those who are healthy.
Topix.net

Medivation Wins Big Again; Gets $110M Up Front in Astellas Deal
When Medivation Inc. gained clearance in March to start its Phase III trial of MDV3100 in prostate cancer, a company executive told BioWorld Today the firm would consider partnering the drug if the right opportunity came along - as it had for Alzheimer's disease drug Dimebon, which scored a potential $725 million deal with Pfizer Inc.
Topix.net

W.Va. woman to star on cereal box
A Fairmont resident is being featured on Special K cereal boxes sold at Kroger stores throughout the region in honor of her fellow breast cancer survivors.
cancercompass.com

Liver X Receptor Agonists Inhibit the Phospholipid Regulatory Gene CTP: Phosphoethanolamine Cytidylyltransferase-Pcyt2
Metabolic pulse-chase experiments demonstrated that 25-hydroxycholesterol (25-OH), the endogenous activator of the liver X receptor (LXR), significantly reduced the biosynthesis of phosphatidylethanolamine via CDP-ethanolamine (Kennedy) pathway at the step catalyzed by CTP: phosphoethanolamine cytidylyltransferase (Pcyt2). In the mouse embryonic fibroblasts C3H10T1/2, the LXR synthetic agonist TO901317 lowered Pcyt2 promoter-luciferase activity in a concentration-dependent manner. Furthermore, 25-OH and TO901317 reduced mouse Pcyt2 mRNA and protein levels by 35–60%. The inhibitory effects of oxysterols and TO901317 on the Pcyt2 promoter function, mRNA and protein expression were conserved in the human breast cancer cells MCF-7. These studies identify the Pcyt2 gene as a novel tar...
Med Worm

AstraZeneca cancels lung cancer drug applications
AstraZeneca PLC said Wednesday it has withdrawn applications for regulatory approval for its lung cancer drug Zactima following disappointing trial results.
Topix.net

RadMD Offers Tips On Optimizing Clinical Trial Efficiency
Lengthier cancer trials and new regulations have forced pharmaceutical companies to look for new ways to minimize costs and increase efficiency.
Topix.net

Best Practices In Breast, Cervical And Colorectal Cancer Screening...
Drawing on years of experience in cancer research and patient care, The University of Texas M. D. Anderson Cancer Center have just released the most comprehensive, risk-based screening guidelines publicly available to date for breast, cervical and colorectal cancers.
Topix.net

Liver Removed And Re-Implanted For Cancer Treatment
Distinguished transplant and cancer surgeon, Alan Hemming, MD, has been recruited to the University of California, School of Medicine to launch a multidisciplinary center for the treatment of advanced liver disease at the UC San Diego Medical Center and Moores UCSD Cancer Center.
Medical News Today

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