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Antigenics Provides Details On GlaxoSmithKline`s Pivotal Malaria Vaccine Trial With QS-21 Adjuvant
Antigenics, Inc. (NASDAQ: AGEN) today indicated that GlaxoSmithKline's (GSK) Phase III malaria vaccine clinical trial, containing Antigenics' QS-21 Stimulon® adjuvant, has enrolled more than 5,000 children to date and is expected to involve up to 16,000 children. The pivotal efficacy study of RTS,S, the world's most clinically advanced malaria vaccine, is ongoing in seven African countries.
Medical News Today

Young Children Exposed to More TV Prone to Aggressive Behavior: Study
A new study shows that three-year-old kids who are exposed to more TV are at an increased risk for exhibiting aggressive behavior. For the study, Jennifer A.
MedicineNet

Prevention of unintentional injuries in children
Abstract: Unintentional injury is a major cause of death in children throughout the world and is responsible for considerable morbidity. All children are vulnerable to injury because their physical, psychological and behavioural characteristics place them at risk in a largely adult world. The children of the poor are even more vulnerable to injury. This article highlights proven strategies for preventing many types of injuries in childhood.
Paediatrics and Child Health

The Caring Generation(TM) Captures #1 Ranking
The Caring Generation captures #1 ranking for Sunday morning programs on 630 KHOW, Denver and continues to build a loyal listening audience. The program introduced May 2009 as Parenting Your Parents targeted adult children caring for parents. ...
newsblaze.com

HHS Secretary Calls On States And Communities To Get Health Coverage To Uninsured Children
HHS Secretary Kathleen Sebelius today called on states and communities to join with HHS to redouble efforts to find and enroll the 5 million children who are currently eligible for Medicaid or the Children's Health Insurance Program (CHIP), but are not yet covered. The Secretary issued this call to action as she opened the National Children's Health Insurance Summit in Chicago, kicking off the nation's largest campaign to find and enroll uninsured children in over a decade.
Medical News Today

CORRECTED: Mom`s antidepressants tied to child health risks
NEW YORK (Reuters Health) - Babies whose mothers used antidepressants during pregnancy visit the doctor more often and have higher risks of certain health problems than other children their age, a new study suggests.
Reuters

The management of paracetamol poisoning
Abstract: Paracetamol poisoning is a common presentation in paediatrics. Toxicity may cause hepatocellular injury, in certain cases progressing to fulminant liver failure. Young children appear less at risk of hepatotoxicity due to an increased metabolic capacity for paracetamol. A single dose of 150 mg/kg can cause hepatocellular damage. Children who ingest multiple supratherapeutic doses can accumulate significant concentrations and may suffer worse outcomes. Older children who intentionally overdose may also suffer worse outcomes, especially those who present late. The risk of hepatotoxicity after a single overdose can be predicted using a widely used nomogram, although it was derived from adult data. The cornerstone of management is administering the antidote N-acetylcysteine when hepatotoxicity is likely to occur. The National Poisons Information Service is available to be consulted at all hours. When severe poisoning is suspected, the child may require referral to a liver unit in
Paediatrics and Child Health

Fabricated or induced illness in children: The paediatrician`s role
Abstract: FII is an uncommon form of child abuse which challenges the very core of the doctor-patient relationship. The unspoken contract of "You tell me what's wrong and I'll do my best to help you." is breached by a parent who fabricates their child's symptoms and sometimes even their physical signs. Anecdotally these diagnoses tend to be very delayed and children often suffer extreme harm in the process. In 2002 RCPCH produced the first definitive guidance on FII. In 2008 the Government produced updated guidance for all professionals which led to RCPCH producing a new Practical Guide in 2009. This paper incorporates much of the 2009 RCPCH guidance and is intended to be a brief guide for the busy Paediatrician who may come across one of these most difficult and time consuming cases.
Paediatrics and Child Health

Improving the outcome of severely head injured children in the UK
Abstract: Traumatic brain injury (TBI) causes significant morbidity and mortality in children. After the primary injury, subsequent physiological insults worsen morbidity and mortality and are particularly common in the pre-hospital setting. Management of severe TBI in hospital is largely focused on the prevention of secondary brain injury, the management of raised intracranial pressure and preservation of cerebral perfusion. Large potential improvements in outcomes for severely brain injured children are possible if the child's entire NHS journey is appreciated. The first hour of this journey is spent outside of hospital where neuroprotection is not provided. Taking clinical expertise to the child, to start neuroprotection shortly after their injury and transfer them directly to definitive care, offers potential to significantly improve outcomes. This could be achieved across the nation by doctor led pre-hospital critical care teams.
Paediatrics and Child Health

Smoking During Pregnancy May Predispose Kids to Behavioral Problems
Women who smoked during pregnancy were more likely to report having children with behavioral problems, and researchers think the reason could be fetal brain damage.
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