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Antigenics Provides Details On GlaxoSmithKline`s Pivotal Malaria Vaccine Trial With QS-21 Adjuvant Antigenics, Inc. (NASDAQ: AGEN) today indicated that GlaxoSmithKline's (GSK) Phase III malaria vaccine clinical trial, containing Antigenics' QS-21 Stimulon® adjuvant, has enrolled more than 5,000 children to date and is expected to involve up to 16,000 children. The pivotal efficacy study of RTS,S, the world's most clinically advanced malaria vaccine, is ongoing in seven African countries. Medical News TodayInspire Completes Patient Enrollment In Three Late-Stage Clinical Trials In Cystic Fibrosis, Dry Eye And Blepharitis Inspire Pharmaceuticals, Inc. (NASDAQ: ISPH) announced today patient enrollment is complete in three of its late-stage clinical trials. 'We are pleased to be executing on our strategic plan with the achievement of these patient enrollment milestones in the clinical development programs for denufosol, PROLACRIAT and AZASITE®, as this places us in a position to have top-line results from all our late-stage clinical programs within 18 months. Medical News TodayAcceleron Pharma Initiates First-in-Human Study Of ACE-041, A Novel Angiogenesis Inhibitor, In Patients With Advanced Cancer Acceleron Pharma, Inc., a biopharmaceutical company developing novel therapeutics that modulate the growth of cells and tissues including red blood cells, bone, muscle, fat, and the vasculature, announced the initiation of a Phase 1 clinical study of ACE-041, a novel angiogenesis inhibitor that binds to and prevents members of the TGF-β superfamily from signaling through the activin receptor-like kinase 1 (ALK1) receptor. Medical News TodayImproving the outcome of severely head injured children in the UK Abstract: Traumatic brain injury (TBI) causes significant morbidity and mortality in children. After the primary injury, subsequent physiological insults worsen morbidity and mortality and are particularly common in the pre-hospital setting. Management of severe TBI in hospital is largely focused on the prevention of secondary brain injury, the management of raised intracranial pressure and preservation of cerebral perfusion. Large potential improvements in outcomes for severely brain injured children are possible if the child's entire NHS journey is appreciated. The first hour of this journey is spent outside of hospital where neuroprotection is not provided. Taking clinical expertise to the child, to start neuroprotection shortly after their injury and transfer them directly to definitive care, offers potential to significantly improve outcomes. This could be achieved across the nation by doctor led pre-hospital critical care teams. Paediatrics and Child HealthAffymax And Takeda Announce HematideT Publication In The New England Journal Of Medicine Affymax, Inc. (Nasdaq:AFFY) and Takeda Pharmaceutical Global Research & Development Center, Inc., announced data from a Phase 2 clinical trial of HematideT showing that Hematide increased hemoglobin and reduced or eliminated the need for blood transfusion in most patients with erythropoietin-induced pure red cell aplasia (PRCA). Medical News TodayAASLD: Direct Antivirals Can Beat HCV Without Interferon (CME/CE) BOSTON (MedPage Today) -- The first clinical trial of direct antiviral drugs against hepatitis C virus (HCV) without interferon was a success, researchers said, though the FDA currently won't permit such a strategy in the U.S. medpagetoday.comNovadaq Expands Q3-09 Financial Results Conference Call to Include Live Webcast TORONTO, ONTARIO--(Marketwire - Nov. 5, 2009) - Novadaq(R) Technologies Inc. (TSX:NDQ), a developer of real-time medical imaging systems for the operating room, announced today that it is expanding the scope of its Q3-2009 financial results conference call, scheduled for November 12, 2009 at 10 AM ET, to include a live webcast presentation. During the webcast, Dr. Arun Menawat, Novadaq President and CEO, will present an update on recent clinical and economic results from studies involving the SPY Imaging System. The webcast will also include a short discussion on the potential for future strategic partnerships. Those planning to participate in the webcast should reserve approximately 45 minutes. Market WireSpicing Up The Effectiveness Of A Potential Disease-Fighter Scientists are reporting development of a nano-size capsule that boosts the body's uptake of curcumin, an ingredient in yellow curry now being evaluated in clinical trials for treatment of several diseases. Their study is in ACS' Journal of Agricultural and Food Chemistry, a bi-weekly publication. Koji Wada and colleagues note that curcumin is a potent antioxidant found in the spice, turmeric. Medical News TodayState Medicaid Coverage for Tobacco-Dependence Treatments --- United States, 2007 The prevalence of tobacco use among adults in the United States has been reduced by half since the 1960s (1,2). Despite this progress, low-income populations, such as Medicaid enrollees, continue to smoke at substantially higher rates than the general population (33% versus 20%) (1). The Public Health Service's Clinical Practice Guideline (2) and the Partnership for Prevention's Call for ACTTION (3) recommend comprehensive insurance coverage of tobacco-dependence treatments without barriers such as copayments, limitations in duration of treatment, prior authorization, and stepped-care therapy. Healthy People 2010 aims to expand coverage of evidence-based treatments for nicotine dependency to all 51 Medicaid programs (objective 27-8b) (4). To monitor progress toward that objective, in 2007, the Center for Health and Public Policy Studies at the University of California, Berkeley, surveyed all 51 Medicaid programs. This report summarizes the results of that survey, which found that 43 (8 Tobacco.orgNeuroVive: NeuroVive Doses Last Patient In Clinical Trial Of Cremophor(R)- Free Cyclosporine I.v. NeuroSTAT(R) NeuroVive Pharmaceutical AB, of Lund, Sweden, announced that on November 3, 2009 it completed the clinical phase of its study investigating tolerability and pharmacokinetics of the cremophor®-free cyclosporine i.v. formula NeuroSTAT®. CEO Eskil Elmér comments that 'This study in 52 healthy subjects is a direct comparison of NeuroVive's injectable cyclosporine product NeuroSTAT® with Novartis's product Sandimmune® Injection. Medical News Today1 2 |
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