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Toxin Alert Inc.: Toxin Alert Inc. Filing Deadline Extended to January 15, 2009
TORONTO, ONTARIO (MARKET WIRE) The Ontario Securities Commission ('OSC') has accepted the request of Toxin Alert Inc. (TSX VENTURE: TOX) that the Management Cease Trade Order under which Toxin Alert is operating to extend to January 15, 2009. The effect of this is that Toxin Alert has until that date to file its audited 2008 financial statements before a general cease trade order would be issued against the company. Toxin Alert intends to close its previously announced private placement on or before January 14, 2009.
Marketwire.com

No Truth to the Fountain of Youth
Editor's Note: We are reposting this essay from our June 2002 issue to accompany our coverage of The Curious Case of Benjamin Button. To read the full position statement on aging and its extensive list of references, follow this link.Efforts to combat aging and extend human life date at least as far back as 3500 B.C., and self-proclaimed experts have touted anti-aging elixirs ever since. Indeed, the prospect of immortality has always had universal appeal, spurring Alexander the Great and Ponce de Leo n to search for the legendary Fountain of Youth and feeding alchemists’ desire to manufacture gold (once believed to be the most potent anti-aging substance in existence). But the hawking of anti-aging “therapies” has taken a particularly troubling turn of late. Disturbingly large numbers of entrepreneurs are luring gullible and frequently desperate customers of all ages to “longevity” clinics, claiming a scientific basis for the anti-aging products they recom
Scientific American

EBs clip CLIPs to growing microtubule ends
Proteins that track growing microtubule (MT) ends are important for many aspects of intracellular MT function, but the mechanism by which these +TIPs accumulate at MT ends has been the subject of a long-standing controversy. In this issue, Bieling et al. (Bieling, P., S. Kandels-Lewis, I.A. Telley, J. van Dijk, C. Janke, and T. Surrey. 2008. J. Cell Biol. 183:1223–1233) reconstitute plus end tracking of EB1 and CLIP-170 in vitro, which demonstrates that CLIP-170 plus end tracking is EB1-dependent and that both +TIPs rapidly exchange between a soluble and a plus end–associated pool. This strongly supports the hypothesis that plus end tracking depends on a biochemical property of growing MT ends, and that the characteristic +TIP comets result from the generation of new +TIP binding sites through MT polymerization in combination with the exponential decay of these binding sites.
.jcb.org

SNPs Of ABC Transporter Genes Linked To Lung Cancer Risk
Individuals with particular variants of certain genes involved in metabolizing the most potent carcinogen found in cigarette smoke have an increased risk of developing lung cancer. That is the conclusion of a new study published in the February 1, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer Society. The study's results may help shed light on how lung cancer develops and could have important implications for preventing smoking-related cancers.
Medicalnewstoday.com

New study examines effects of Graniteville, S.C., chlorine gas disaster
(IQ Solutions, Inc.) A new study examining the aftereffects of a chlorine gas disaster in a South Carolina town gives larger metropolitan areas important insight into what to expect and how to prepare emergency response systems for an accidental or terrorist release of the potentially deadly gas. The study is now available in the January 2009 issue of the American Journal of Emergency Medicine.
foe.co.uk

Study investigates the cost effectiveness of spinal surgery
A study by researchers at Rush University Medical Center suggests that for patients with spinal stenosis, a laminectomy, or surgical removal of some soft bone and tissue, is a reasonable value. However, for patients with spinal stenosis with associated slipped vertebrae, the benefits of spinal fusion surgery may not be enough to offset costs. The study is published in the Dec. 16 issue of the Annals of Internal Medicine.
Eurekalert.org

Nutrigenomics -- developing personalized diets for disease prevention
The emerging field of nutrigenomics, which aims to identify the genetic factors that influence the body's response to diet and studies how the bioactive constituents of food affect gene expression, is explored in a series of provocative, interdisciplinary reports and analyses in the December 2008 special issue.
Eurekalert.org

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